Bills rally from a 15-point fourth-quarter hole to stun Baltimore 41-40 in a Week 1 classic, rewriting late-game fantasy appeal for Allen and company. Baltimore’s high-scoring pace is clear, but the win probability tilted Buffalo’s way late, with a backfield still mapping out roles and a defense that stretched for big plays.

In Minnesota, Jefferson endured drops but Addison flashed as a high-upside rookie, Pitts finally looked the part for Atlanta with big target counts, Flowers erupted for Baltimore, and Seattle’s JSN dominated targets. The opening slate sets up a wave of week-to-week pivots for fantasy managers.

Brock Purdy’s turf-toe setback reshapes San Francisco’s fantasy landscape as Christian McCaffrey and Deebo Samuel carry heavier workloads while the backfield breathes. Tyreek Hill’s trade chatter lingers in the air as teams weigh capital against risk. Jahmyr Gibbs surges in value behind the CMC-thriving narrative, while Drake London and Nico Collins emerge as practical, upside-wue targets for Week 2 rosters.

Across the board, savvy managers are slicing rosters to pounce on rising players (Gibbs, London, Nico Collins) and to pivot away from overcommitted veterans. The episode blends injury volatility with actionable trades and tight-end/value plays, offering a concrete blueprint for bold, yet disciplined, Week 2 decision-making.

Tyreek Hill’s off‑field situation dominates the slate as the NFL examines domestic allegations tied to Dolphins personnel. Miami has not shown immediate willingness to part with Hill, but the uncertainty drags his fantasy ceiling down in the short term even as his talent remains undeniable. Trade rumors will keep managers wary, with some evaluating quick sell‑high pivots while others hedge by targeting safer holds and savvy buys in Week 2.

On the field, London looks ready to return for Week 2 and Xavier Worthy’s absence tightens the door for Texans and other pass catchers, while Devonta Smith and Garrett Wilson sit squarely in the top tier of Week 2 lineups. James Cook hamstring updates, Brock Purdy backup risk, and Nico Collins health chatter all shape the waiver and trade landscape, alongside bold buy lows and strategic bench moves that could redefine fantasy value as Week 2 unfolds.